FTIR- and UHPLC-Q-Orbitrap HRMS-Based Metabolomics of Sonchus arvensis Extracts and Evaluation of Their Free Radical Scavenging Activity

Sonchus arvensis, known as sowthistle, belongs to Asteraceae and contains numerous phenolic acids flavonoids that exhibit antioxidants. The type of extraction solvent will affect biological activity level, resulting in different metabolite profiles metabolomics approaches can evaluate by fingerprint analysis using FTIR spectrophotometry UHPLC-Q-Orbitrap HRMS. Furthermore, the spectra profile HRMS were grouped principal component (PCA). This study aimed clustering S. arvensis extracts based on extracting solvents detected metabolites free radical scavenging activity. 50% ethanol extract gave higher more than p.a. water extracts. It indicates is affected contained extract. Using a combination peak area identified metabolites, be according solvent. Thus, affects composition levels.